The mission of our team is to characterize disease-specific induced pluripotent stem cell (iPSC) lines, which were mainly deposited in RIKEN cell bank, for their differentiation potency (esp. targeted cell types in each disease) and genomic sequence (esp. responsible genes in each disease).
Also, we aim to generate genetically modified iPSC lines including mutation-introduced iPSC lines from healthy-donor iPSC lines, mutation-corrected iPSC lines from disease-specific iPSC lines, and reporter-introduced iPSC lines.
Through these research and development, we will provide the information accompanying to each iPSC line and the cell lines that we will develop through RIKEN cell bank.