Research Articles

2023

Nakade K, Tsukamoto S, Nakashima K, An Y, Sato I, Li J, Shimoda Y, Hemmi Y,
Miwa Y, Hayashi Y. Efficient selection of knocked-in pluripotent stem cells
using a dual cassette cellular elimination system. Cell Rep Methods. 2023 Dec
18;3(12):100662. doi: 10.1016/j.crmeth.2023.100662. Epub 2023 Dec 11. PMID:
38086384; PMCID: PMC10753384.

Takahi M, Taira R, Onozuka J, Sunamura H, Kondow A, Nakade K, Nakashima K,
Sato I, Hayashi Y, Patra C, Ohnuma K. Xenograft of human pluripotent stem cell-
derived cardiac lineage cells on zebrafish embryo heart. Biochem Biophys Res
Commun. 2023 Sep 24;674:190-198. doi: 10.1016/j.bbrc.2023.06.040. Epub 2023 Jun 14. PMID: 37532637.

2022

Song D, Takahashi G, Zheng YW, Matsuo-Takasaki M, Li J, Takami M, An Y, Hemmi
Y, Miharada N, Fujioka T, Noguchi M, Nakajima T, Saito MK, Nakamura Y, Oda T,
Miyaoka Y, Hayashi Y. Retinoids rescue ceruloplasmin secretion and alleviate
oxidative stress in Wilson’s disease-specific hepatocytes. Hum Mol Genet. 2022
Apr 7:ddac080. doi: 10.1093/hmg/ddac080. Epub ahead of print. PMID: 35388883.

Shimoda Y, Murakoshi N, Mori H, Xu D, Tajiri K, Hemmi Y, Sato I, Noguchi M,
Nakamura Y, Hayashi Y, Ieda M. Generation of a human induced pluripotent stem
cell line derived from a patient with dilated cardiomyopathy carrying LMNA
nonsense mutation. Stem Cell Res. 2022 Jul;62:102793. doi:
10.1016/j.scr.2022.102793. Epub 2022 Apr 27. PMID: 35500377.

Anh LPH, Nishimura K, Kuno A, Linh NT, Kato T, Ohtaka M, Nakanishi M,
Sugihara E, Sato TA, Hayashi Y, Fukuda A, Hisatake K. Downregulation of Odd-
Skipped Related 2, a Novel Regulator of Epithelial-Mesenchymal Transition,
Enables Efficient Somatic Cell Reprogramming. Stem Cells. 2022 Apr
29;40(4):397-410. doi: 10.1093/stmcls/sxac012. PMID: 35385105.

Shimizu T, Matsuo-Takasaki M, Luijkx D, Takami M, Arai Y, Noguchi M, Nakamura
Y, Hayata T, Saito MK, Hayashi Y. Generation of human induced pluripotent stem
cell lines derived from four DiGeorge syndrome patients with 22q11.2 deletion.
Stem Cell Res. 2022 May;61:102744. doi: 10.1016/j.scr.2022.102744. Epub 2022 Mar 9. PMID: 35292424.

Aizawa S, Nishimura K, Mondejar GS, Kumar A, Bui PL, Tran YTH, Kuno A,
Muratani M, Kobayashi S, Nabekura T, Shibuya A, Sugihara E, Sato TA, Fukuda A,
Hayashi Y, Hisatake K. Early reactivation of clustered genes on the inactive X
chromosome during somatic cell reprogramming. Stem Cell Reports. 2022 Jan
11;17(1):53-67. doi: 10.1016/j.stemcr.2021.11.008. Epub 2021 Dec 16. PMID:
34919813; PMCID: PMC8758948.

2021

Borisova E, Nishimura K, An Y, Takami M, Li J, Song D, Matsuo-Takasaki M, Luijkx D, Aizawa S, Kuno A, Sugihara E, Sato T, Yumoto F, Terada T, Hisatake K, Hayashi Y. Structurally-discovered KLF4 variants accelerate and stabilize reprogramming to pluripotency. iScience. 2021 Dec 21:103525. doi.org/10.1016/j.isci.2021.103525.

Ugawa M, Kawamura Y, Toda K, Teranishi K, Morita H, Adachi H, Tamoto R,
Nomaru H, Nakagawa K, Sugimoto K, Borisova E, An Y, Konishi Y, Tabata S,
Morishita S, Imai M, Takaku T, Araki M, Komatsu N, Hayashi Y, Sato I, Horisaki
R, Noji H, Ota S. In silico-labeled ghost cytometry. Elife. 2021 Dec
21;10:e67660. doi: 10.7554/eLife.67660. PMID: 34930522; PMCID: PMC8691837.

Song D, Zheng YW, Hemmi Y, An Y, Noguchi M, Nakamura Y, Oda T, Hayashi Y.
Generation of human induced pluripotent stem cell lines carrying homozygous JAG1
deletions. Stem Cell Res. 2021 Oct 26;57:102588. doi: 10.1016/j.scr.2021.102588.
Epub ahead of print. PMID: 34736037.

Tsukamoto S, Nakade K, Wakabayashi T, Nakashima K, Takami M, Hemmi Y, Kuramochi Y, Shimizu T, Arai Y, Matsuo-Takasaki M, Noguchi M, Nakamura Y, Miwa Y, Hayashi Y. Generation of two ISL1-tdTomato reporter human induced pluripotent stem cell lines using CRISPR-Cas9 genome editing. Stem Cell Res. 2021 May;53:102363. doi: 10.1016/j.scr.2021.102363. Epub 2021 Apr 22. PMID: 34087992.

Kuramochi Y, Awaya T, Matsuo-Takasaki M, Takami M, An Y, Li J, Hemmi Y, Wakabayashi T, Arai Y, Inoue J, Noguchi M, Nakamura Y, Asaka I, Akimoto K, Saito MK, Hayashi Y. Generation of two human induced pluripotent stem cell lines derived from two X-linked adrenoleukodystrophy patients with ABCD1 mutations. Stem Cell Res. 2021 May;53:102337. doi: 10.1016/j.scr.2021.102337. Epub 2021 Apr PMID: 33901816.

2020

Arai Y, Takami M, An Y, Matsuo-Takasaki M, Hemmi Y, Wakabayashi T, Inoue J, Noguchi M, Nakamura Y, Sugimoto K, Takemura T, Okita K, Osafune K, Takasato M, Hayata T, Hayashi Y.
Generation of two human induced pluripotent stem cell lines derived from two juvenile nephronophthisis patients with NPHP1 deletion.
Stem Cell Res. 2020 May;45:101815. doi: 10.1016/j.scr.2020.101815. Epub 2020 Apr 21. PMID: 32361464

2019

Fukuda A, Honda S, Fujioka N, Sekiguchi Y, Mizuno S, Miwa Y, Sugiyama F, Hayashi Y, Nishimura K, Hisatake K. Non-invasive in vivo imaging of UCP1 expression in live mice via near-infrared fluorescent protein iRFP720. PLoS One. 2019 Nov 15;14(11):e0225213. doi: 10.1371/journal.pone.0225213. eCollection 2019. PubMed PMID: 31730675.

Nishimura K, Ishiwata H, Sakuragi Y, Hayashi Y, Fukuda A, Hisatake K. Live-cell imaging of subcellular structures for quantitative evaluation of pluripotent stem cells. Sci Rep. 2019 Feb 11;9(1):1777. doi: 10.1038/s41598-018-37779-x. PubMed PMID: 30741960; PubMed Central PMCID: PMC6370783.

Ueki R, Atsuta S, Ueki A, Hoshiyama J, Li J, Hayashi Y, Sando S. DNA aptamer assemblies as fibroblast growth factor mimics and their application in stem cell culture. Chem Commun (Camb). 2019 Feb 26;55(18):2672-2675. doi: 10.1039/c8cc08080a. PubMed PMID: 30746545.

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2005