Category Archives: News

A co-authored article has been published with my former lab, the gene regulation lab at University of Tsukuba. Live-cell imaging of subcellular structures for quantitative evaluation of pluripotent stem cells Ken Nishimura, Hiroshi Ishiwata, Yuta Sakuragi, Yohei Hayashi, Aya Fukuda & Koji Hisatake Scientific Reports volume 9, Article number: 1777 (2019)  

Our article, “Automated adherent cell elimination by a high-speed laser mediated by a light-responsive polymer”, has been selected as an editors’ pick in Communications Biology first year anniversary collection. I’m very happy that the article is highly evaluated.

RIKEN is currently accepting applications for the FY 2020 Special Postdoctoral Researcher (SPDR) Program, from young, creative, independent researchers who will be a powerful force in furthering RIKEN’s research activities. Our lab has joined this program as a host lab. So far, no candidates are assigned. Please let us know if you are eligible and interested. http://www.riken.jp/en/careers/programs/spdr/career2020/

We have received a research grant from iPS Academia Japan, Inc http://ips-cell.net/e/ It’s very honor to receive it. We will use the grant for our valuable studies on iPSCs efficiently.  

We have published a new research article in Communications Biology, a newly launched journal from Springer Nature. We have developed a system of automated adherent cell elimination by a high-speed laser mediated by a light-responsive polymer, called LiLACK (Laser-induced, Light-responsive- polymer-Activated, Cell Killing). We have demonstrated that human induced pluripotent stem cells (hiPSCs) maintained their pluripotency and self-renewal during long-term culture using this system in each passage for sectioning. Furthermore, combined with deep machine-learning analysis on fluorescent and phase contrast images, we have developed a label-free and automatic cell processing system by eliminating unwanted spontaneously differentiated cells in undifferentiated hiPSC culture conditions.     Full article can be read below the Continue reading A new research article has been published→

On November 7, Yohei Hayashi gave an invited lecture at Joint Japan-Spain Symposium on Medical Research. This symposium was held in celebrating the 150th Anniversary of Japan-Spain diplomatic relations and was sponsored by Japan AMED (Agency for Medical Research and Development) and Ministry of Science, Innovation and Universities in Spain with the support of the embassy of Japan in Madrid.  

One of our team’s trainee student, Evgeniia “Jenny” Borisova”, is selected for recipients of Otsuka Toshimi Foundation scholarship. It is very honer to her and grateful for the foundation. Congratulations, Jenny!

On Sep 5, I will present a poster at the 5th TERMIS World Congress in Kyoto.

On August 9, an interview article of Yohei Hayashi was published on page 5 of  Nikkei Industrial NewsPaper. Thank you, Inomata-san (the writer)!

From my previous laboratory (Gene regulation laboratory in University of Tsukuba), an article titled “Live cell imaging of X chromosome reactivation during somatic cell reprogramming” has been published. We generated female mouse embryonic stem cells (ESCs) that carry two-colored fluorescent protein expression on both alleles in X chromosomes. The ESC clones, which initially expressed both EGFP and hKO, inactivated one of the fluorescent protein genes upon differentiation, indicating that the EGFP and hKO genes are subject to X chromosome inactivation (XCI). When the derived somatic cells carrying the EGFP gene on the inactive X chromosome (Xi) were reprogrammed into iPSCs, the EGFP gene on the Xi was reactivated when pluripotency marker Continue reading Published a co-authored article→